The Misa River has its source in the mountains of the small village of Arcevia and runs through the city of Senigallia. It flows for miles through a fertile valley protected by the hilly landscape, rich in villages, historic sites, river landscapes, cultivated areas, and wild, fascinating trekking trails. In addition to Misa, the area includes the rivers Cesano, Metauro, Esino and Musone and, from north to south, the rivers that flow across the region's comb-like valleys. Each river has a peculiar history, a variety of small communities, and a great naturalistic heritage.

From the balcony of Scapezzano, in a crisp, windy day, you can see the Croatian coast and the Velebit Mountains. Centuries-old olive groves, vineyards and cultivated fields - wheat, sunflowers, barley, spelt – cover the slopes from the Adriatic shore. The reconversion of the land has fostered the diffusion of organic farming, in the area of Senigallia, Roncitelli, Ostra, Corinaldo, Belvedere Ostrense, Ostra Vetere, Piticchio, Arcevia, and Castelleone di Suasa. It is the contemporary evolution of the sharecropping culture made of aesthetic ethics and care for the people and the environment - farmyards, partitions and boundaries, crop rotation, cohabitation of trees and native species. It is a boast for the Marche region and its enterprises and a symbol of Made in Italy.

It is an infrastructure of devotion. It bows in front of the holy shrines along white country roads. It enters small shrines and churches where the May Rosary is recited. It builds Cathedrals for traveling pilgrims. Spirituality is felt, heard and seen in the landscape, in the small local communities, in the works of art of museums and art galleries, in the blue mountains that frame the Apennine ridge. There are places of contemplation, such as Monasterio delle Grazie in Senigallia, the birthplace of Saint Maria Goretti in Corinaldo, Santuario della Rosa and the collection of votive offerings in Ostra, Abbazia di Sant’Elena in Rosora, the Shrine of the Holy House in Loreto.

Historic wineries and new stories of land and business. Olive groves and orchards of ancient species. Mills for the recovery of ancient grains and artisanal stone grinding. Pasta factories with traditional productions and old drying techniques. Plantations of botanical essences and medicinal plants for healing, cosmetics and the soap art of natural wellness. Inns, taverns, shops, outlets, factories, bars and meeting places. They are cozy and comfortable centers of wisdom and of ancient and contemporary knowledge.

Molino Paolo Mariani, Lavandeto, L'Artigiana del naturale, Pietro Massi, La Terra e il Cielo, Frantoio Lugliaroli, Frantoio Montedoro, Enoteca Galli, Patatas Nana, Sena Gallica